Matthew Davis is a Senior Partner at Flagship Pioneering where he leads the AI strategy for a portfolio of breakthrough biotech innovation companies.

Prior to joining Flagship, Matt led AI/ML research and development at publicly traded companies in the human genetics deep technology spaces. He served as Head of AI & Data at Invitae, where he led strategic business development in AI/ML and grew a team to apply machine learning to clinical interpretation, scalable operations, and personalized patient insights. His team’s application of probabilistic machine learning to variant interpretation led to the resolution of tens of thousands of clinical human variants. He later led the technical transformation of Sema4/GeneDx as Chief Product and Technology Officer.

He began his career at IBM working in Linux development and high-performance computing, which led him to academic research in systems and computational biology. He worked with pioneers at UT Austin and UC Berkeley applying machine learning to high throughput morphological phenotyping, x-ray crystallography, and transcriptional regulation.

Matt returned to computer science as a group leader at IBM Research, founding a team to research multimodal AI agents and human-computer interaction. In addition to developing several enterprise software products in this space, Matt continued to author papers and patents in the fields of NLP, AI, HCI, and biology. He holds a Bachelor’s degree from UT Austin and a Ph.D. from UC Berkeley.